Take note of the differences between the proposed and final versions of the ICD-10-CM code set. The ICD-10-CM Coordination & Maintenance Committee added six new codes that describe a personal history of gender transition (Z87.8901-Z87.8909 and Z87.893) that were not featured in the April release of the proposed codes. In addition, the committee changed course on its proposal to delete C75.9 (Malignant neoplasm of endocrine gland, unspecified).
Released Friday, June 5, 2026, the update includes 190 new codes, 30 invalidated codes and four revised codes. The changes will take effect Oct. 1, 2026.
Found in Chapter 21: Factors influencing health status and contact with health services (Z00-Z99), a new code will be added for Z86.17 (Personal history of Clostridioides difficile infection).
Patients with resolved C. diff are common, experts note, and there is no good code to capture this currently. The patients are at risk for reinfection, rehospitalization and further gastrointestinal complications, making the ability to code history of C. diff important.
Also helpful for providers: new Z codes for body mass index (BMI):
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Z68.18 (BMI 18.4 or less, adult)
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Z68.19 (BMI 18.5-19.9, adult)
Lower BMI is associated with higher risk for skin breakdown, immunodeficiency and other poor outcomes, experts note.
An expansion of cardiomyopathy codes I42.0 and I42.8 will allow reporting of familial-genetic dilated cardiomyopathy and arrhythmogenic cardiomyopathy. A new code, I47.22, tracks catecholaminergic polymorphic ventricular tachycardia (CPVT), a condition in which a structurally normal heart lapses into dangerous, irregular heart rhythms during stress or exercise. Also, look for new codes for other heart arrhythmias, including Brugada syndrome (I49.81) and ventricular bigeminy (I49.82).
Physician documentation has become increasingly specific for many conditions, including cardiomyopathies, experts note.
A new code for moderate hepatic fibrosis (K74.0A) allows more accurate coding of the liver disorder. This will be helpful since there are currently only codes for unspecified, early and advanced.
Notable changes from proposed
The final code changes did not include the proposed removal of C75.9 (Malignant neoplasm of endocrine gland, unspecified).
However, the final set removes Z87.890 (Personal history of sex reassignment).
In its place, six related codes were added:
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Z87.8901 (Personal history of social gender transition)
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Z87.8902 (Personal history of medical gender transition)
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Z87.8903 (Personal history of surgical gender transition)
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Z87.8904 (Personal history of intersex surgery)
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Z87.8909 (Personal history of unspecified gender transition)
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Z87.893 (Personal history of gender detransition)
New endocrine codes E89.830 and E89.838 allow tracking of hypoglycemia occurring after bariatric and other surgeries.
Providers will have five new codes for sinusitis related to dental infections, damage and procedures, such as implants.
- J34.830 (Odontogenic sinusitis, maxillary sinus)
- J34.831 (Odontogenic sinusitis, ethmoid sinus)
- J34.832 (Odontogenic sinusitis, frontal sinus)
- J34.833 (Odontogenic sinusitis, sphenoid sinus)
- J34.839 (Odontogenic sinusitis, unspecified)
Also, look for new digestive system codes for prevesical pelvic abscess (K6A.01) and other pelvic abscesses and diseases not elsewhere specified.
In the musculoskeletal chapter, expanded codes for plantar fasciitis (M67.A-) and plantar fascial fibromatosis (M72.2-) as well as other osteomyelitis (M86.8X-), will allow coding specific to laterality. A new code, M04.3 reports the severe, adult onset autoinflammatory disease known as VEXAS syndrome.
New genitourinary codes report intraoperative and post-procedural nipple ischemia (N99.860) and necrosis (N99.861).
New congenital codes will report familial cancer syndrome with pathogenic BRCA1 (QA1.790) and BRCA2 (QA1.791).
Another finalized ICD-10-CM update adds new war-related codes in Chapter 21: